PD Dr. med. Matthias C. Grieshaber

2012
Habilitation – Venia legendi (Privatdozent) für das Fach Ophthalmologie der Universität Basel (Habilitationschrift: Canaloplasty – a new surgical approach to restore physiological aqueous outflow in glaucoma patients)

2008
Facharzttitel Ophthalmochirurgie FMH

2006
Diploma in Clinical Sciences Assessment, International Council of Ophthalmology (ICO), London, UK

2004-2006
Clinical Fellowship, klinische Glaukomforschung, Universitäts-Augenklinik Basel (Prof. Josef Flammer)

2004
Facharzttitel Ophthalmologie FMH
Diploma and Fellow, European Board of Ophthalmology (FEBO), Paris
Diploma in Basic Science Assessment, International Council of Ophthalmology (ICO), London, UK

2001-2003
Clinical Fellowship Vorderabschnitts- und Glaukomchirurgie, Traumatologie, Medical University of Southern Africa, Pretoria, South Africa (Prof. Robert Stegmann).

1999
Doktortitel der Universität Zürich

1998
Approbation der Universität Zürich

1992-1998
Studium der Humanmedizin an der Universität Zürich und Pierre et Marie Curie, Paris

1978 – 1992
Schulen und Matura in Schaffhausen, Pitzer College, Claremont, USA

Seit 2014
Ärztlicher Leiter OP Zentrum Schaffhausen

2009-2014
Belegarzt Hirslanden Klinik Belair

2008
Praxisübernahme Dr. Eberli, Schaffhausen

Seit 2018
Kaderarzt (Teilzeit) spez. Vorderabschnitts- und Glaukomchirurgie, Universitäts-Augenklinik Basel / Belegarzt Kantonsspital Baselland Liestal, spez. Katarakt- und Glaukomchirurgie

2006-2017
Oberarzt, spez. Vorderabschnitts- und Glaukomchirurgie, Universitäts-Augenklinik Basel

2003-2004
Assistenzarzt, Universitäts-Augenklinik Zürich

2001-2003
Registrar, Ophthalmology, Medical University of Southern Africa, Pretoria, South Africa (Prof. Robert Stegmann)

2000
Assistenzarzt, Ophthalmologie, Universitäts-Augenklinik Zürich (Prof. Theo Seiler)

1999
Assistenzarzt, Chirurgie, Kantonsspital Baden (Prof. Säuberli)

• Kantonale Ärztegesellschaft Schaffhausen
• Schweizerische Ärztegesellschaft (FMH)
• Schweizerische Ophthalmologische Gesellschaft (SOG)
• European Society of Cataract and Refractive Surgeons (ESCRS)
• European Glaucoma Society (EGS)
• European Association for Vision and Eye Research (EVER)
• American Academy of Ophthalmology (AAO)

2012
International Scholar Award, American Academy of Ophthalmology (AAO), San Francisco

2009
International Educational Award, American Academy of Ophthalmology (AAO), San Francisco

1999
Semesterpreis (Beste Dissertation), Medizinische Fakultät, Universität Zürich (1999)

Grundlegende sowie klinisch angewandte Forschung auf dem Gebiet des Grünen Stars (Glaukom).

Regelmässiger Gutachter für internationale ophthalmologische Zeitschriften (alphabetisch):

• Acta Ophthalmologica Scandinavica
• British Journal of Ophthalmology
• Current Eye Research
• European Journal of Ophthalmology
• Graefe’s Archive for Clinical and Experimental Ophthalmology
• International Journal of Ophthalmology
• International Journal of Clinical Ophthalmology and Visual Sciences
• Investigative Ophthalmology and Visual Science (IOVS)
• Indian Journal of Ophthalmology                                                                   
• Journal of Glaucoma
• Journal of Cataract and Refractive Surgery (JCRS)
• Head and Face Medicine
• Klinische Monatsblätter für Augenheilkunde
• Ophthalmology
• Ophthalmic Research

Seit 2014
Privatdozent für Ophthalmologie, Universität Basel

Seit 2006
Regelmässige Supervision von Post-doc Studenten und Doktoranden, Universität Basel

Seit 2014
Prüfungsexperte, Schweizerische (FMH) und europäische (EBO) Facharztprüfung in Ophthalmologie

Seit 2012
Präsident, Verein zur Förderung der Weiterbildung, Basel

Seit 2012
Präsident, Verein Pro Addis Abeba, Basel

• Deutsch
• Französisch
• Englisch
• Spanisch

> Pubmed

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Original publications in peer reviewed journals als Erst- oder Letztautor

1. Grieshaber MC, Pienaar A, Stegmann R. Flap-sparing canaloplasty: a modified approach to Schlemm’s canal. Graefes Arch Clin Exp Ophthalmol. 2019 Aug;257(8):1729-1732. Epub 2019 May 6.

2. Grieshaber MC. Stegmann Canal Expander for canaloplasty: A novel technique. Eur J Ophthalmol. 2018 Jul;28(4):472-478. doi: 10.1177/1120672117753699. Epub 2018 Mar 19
3. Nützi C, Schötzau A, Grieshaber MC. Structure and Function Relationship of Activated Retinal Glia in Primary Open-Angle Glaucoma Patients. J Ophthalmol. 2017;2017:7043752.

4. Grieshaber MC, Schoetzau A, Grieshaber HR, Stegmann R. Canaloplasty with Stegmann Canal Expander for primary open-angle glaucoma: two-year clinical results. Acta Ophthalmol. 2017 Aug;95:503-508.
5. Grieshaber MC, Grieshaber HR, Stegmann R. A New Expander for Schlemm Canal Surgery in Primary Open-angle Glaucoma-Interim Clinical Results. J Glaucoma. 2016 Aug;25(8):657-62.
6. Brandao LM, Schötzau A, Grieshaber MC. Suture Distension of Schlemm’s Canal in Canaloplasty: An Anterior Segment Imaging Study. J Ophthalmol. 2015;2015:457605. doi: 10.1155/2015/457605. Epub 2015 May 19

7. Grieshaber MC, Sunaric-Mégevand G, Ronzani M, Maurer P, Fehlker M. [Usability testing of the canal expander – a new implant for canaloplasty. Klin Monbl Augenheilkd. 2015 Apr;232(4):432-7

8. Nützi C, Orgül S, Schötzau A, Grieshaber MC. Predictability of Morphological Changes of the Anterior Chamber Angle after Laser. Iridotomy by Ultrasound Biomicroscopy. Klin Monbl Augenheilkd. 2015 Apr;232(4):419-426.

9. Grieshaber MC. [Channelography and mechanism of action in canaloplasty]. Ophthalmologe. 2015 Apr;112(4):319-24.
10. Grieshaber MC, Stegmann R, Grieshaber HR, Meyer P. Novel device for expanding Schlemm’s canal: a morphological study. Br J Ophthalmol. 2015 Jul;99(7):875-7. Epub 2015 Jan 18. 

11. Grieshaber MC, Peckar C, Pienaar A, Koerber N, Stegmann R. Long-term results of up to 12 years of over 700 cases of viscocanalostomy for open-angle glaucoma. Acta Ophthalmol. 2014 Oct 1. [Epub ahead of print]

12. Grieshaber MC, Moramarco F, Schoetzau A, Flammer J, Orguel S. Detection of retinal glial cell activation in glaucoma by time domain optical coherence tomography. Klin Monbl Augenheilkd. 2012 Apr;229(4):314-8. Epub 2012 Apr 11.

13. Grieshaber MC, Schoetzau A, Flammer J, Orgül S. Postoperative microhyphema as a positive prognostic indicator in canaloplasty. Acta Ophthalmol. 2013 Mar;91(2):151-6. Epub 2011 Dec 9.
14. Grieshaber MC, Pienaar A, Olivier J, Stegmann R. Canaloplasty in primary open-angle glaucoma: Long-term outcome / Br J Ophthalmol./ 94(11): 1478-82 / 2010.
15. Grieshaber MC, Fraenkl S, Schoetzau A, Flammer J, Orgul S. Circumferential viscocanalostomy and suture canal distension (canaloplasty) for whites with open-angle glaucoma / J Glaucoma / Jun 23, Epub ahead / 2010.
16. Grieshaber MC, Pienaar A, Olivier J, Stegmann R: Comparing two tensioning suture sizes for 360 degree viscocanalostomy (canaloplasty): a randomized controlled trial. Eye (London). Jul 24(7): 1220-6 / 2010.
17. Grieshaber MC, Pienaar A, Olivier J, Stegmann R: Clinical evaluation of the aqueous outflow system in primary open-angle glaucoma for canaloplasty. Invest Ophthalmol Vis Sci. Mar; 51 (3): 1498-504 / 2010.
18. Grieshaber MC, Pienaar A, Olivier J, Stegmann R: Channelography: Imaging of the aqueous outflow pathway with flexible microcatheter and fluorescein in canaloplasty. Klin Monatsbl Augenheilkd. 245-248 / 2009.
19. Grieshaber MC, Olivier J, Pienaar A, Stegmann R / Capsular opacification after vitreous-sparing cataract surgery in children / Klin Monatsbl Augenheilkd. 226 (4): 258-263 / 2009.
20. Grieshaber MC, Katamay R, Gugleta K, Kochkorov A, Flammer J, Orgul S / Relationship between ocular pulse amplitude and systemic blood pressure measurements / Acta Ophthalmol 2009, May 87(3) 329-34 / 2009.
21. Grieshaber MC, Schoetzau A, Zawinka C, Flammer J, Orgul S: Effect of central corneal thickness on dynamic contour tonometry and Goldmann applanation tonometry in primary open-angle glaucoma. Arch Ophthalmol. Jun;125(6):740-4 / 2007.
22. Grieshaber MC, Orgul S, Schoetzau A, Flammer J: Relationship between retinal glial cell activation in glaucoma and vascular dysregulation. J Glaucoma. Mar;16(2):215-9 / 2007.
23. Grieshaber MC, Koçak I, Dubler B, Flammer J, Orgül S: Retrobulbar blood flow in patients with cataract. Br J Ophthalmol. 90(12):1512-5 / 2006.
24. Grieshaber MC, Stegmann R: Penetrating eye injuries in South African children: aetiology and visual outcome. Eye. 20(7):789-95 / 2006.
25. Grieshaber MC, Pienaar A, Stegmann R: Posterior vertical capsulotomy with optic entrapment of the intraocular lens in congenital cataracts – prevention of capsule opacification. J Cataract Refract Surg./ 31(5):886-94 / 2005
26. Grieshaber MC, Niemeyer G: [Leber congenital amaurosis: diagnosis, follow-up and differential diagnosis]. Klin Monatsbl Augenheilkd. / 212(5):309-10 / 1998.

Original publications in peer reviewed journals as co-author

1. Graeff E, Grieshaber MC, Tzankov A, Meyer P. [Persisting lesion of the conjunctiva. A masquerade syndrome?]. Ophthalmologe. 2016 Feb;113(2):164-7.

2. Jacobs H, Grieshaber MC, Schneider U, Henrich PB, Goldblum D. Toric intraocular lenses: a valuable method for correcting corneal astigmatism. Klin Monbl Augenheilkd. 2015 Apr;232(4):372-4. doi: 10.1055/s-0035-1545815. Epub 2015 Apr 22. German. 

3. Weiss J, Fränkl SA, Flammer J, Grieshaber MC, Hollo G, Teuchner B, Haefeli WE. No difference in genotype frequencies of polymorphisms of the nitric oxide pathway between Caucasian normal and high tension glaucoma patients. Mol Vis. 2012;18:2174-81. Epub 2012 Aug 7.
   
   
4. Mikheytseva I, Lipovetskaya E, Kopp O, Mozaffarieh M, Grieshaber MC, Flammer J, Meyer P: Adrenaline-induced chronic ocular hypertension in adult rabbits / Klin Monbl Augenheilkd. / 226(4):332-6 / 2009.
   
   
5. Meyer P, Salzer P, Grieshaber MC, Meyer A. / Contribution to comparative ophthalmo-morphology: the eye of the brown trout / Klin Monbl Augenheilkd. 226(4):337-40 / 2009.
   
   
6. Katamay R, Grieshaber MC, Weich C, Flammer J, Orgül S: Central corneal thickness and retrobulbar blood flow in glaucoma patients. Klin Monatsbl Augenheilkd. 225(5):346-8 / 2008.
   
   
7. Gugleta K, Mehling M, Kochkorov A, Grieshaber MC, Katamay R, Flammer J, Orgül S, Kappos L: Pattern of macular thickness changes measured by ocular coherence tomography in patients with multiple sclerosis. / Klin Monatsbl Augenheilkd. / 225(5):408-12 / 2008.
   
   
8. Kovalska M, Grieshaber MC, Schötzau A, Katamay R, Hauenstein D, Flammer J, Orgül S: Detection of visual field progression in glaucoma. Klin Monatsbl Augenheilkd. 225(5):342-5. / 2008
   
   

Case Reports, Reviews, Editorials, Letters to the Editor in Peer Reviewed-Journals 

1. Grieshaber MC. Viscocanalostomy and Canaloplasty: ab Externo Schlemm’s Canal Surgery. Dev Ophthalmol. 2017;59:113-126
   
   
2. Todorova MG, Cámara RJ, Miny P, Palmowski-Wolfe AM. Anterior segment dysgenesis associated with Williams-Beuren syndrome: a case report and review of the literature. BMC Ophthalmol. 2014 May 21;14:70. doi: 10.1186/1471-2415-14-70. Review.
   
   
3. Grieshaber MC., Brandao LM, Orgul S, Klin Monbl Augenheilkd. Hemorrhagic descemet membrane detachment after classic canaloplasty. 2014 Apr;231(4):348-50. doi: 10.1055/s-0034-1368273. Epub 2014 Apr 25.
   
   
4. Brandào LM, Grieshaber MC. Update on Minimally Invasive Glaucoma Surgery (MIGS) and New Implants. J Ophthalmol. 2013;2013:705915. doi: 10.1155/2013/705915. Epub 2013 Nov 27. Review.
   
   
5. Grieshaber MC. Ab externo Schlemm’s canal surgery: viscocanalostomy and canaloplasty. Dev Ophthalmol. 2012;50:109-24. doi: 10.1159/000334793. Epub 2012 Apr 17. Review.
   
   
6. Todorova MG, Parsa CF, Grieshaber MC. Ciliary body clefting accompanied by rupture of the trabecular meshwork in congenital glaucoma. Arch Ophthalmol. 2012 Apr;130(4):534. doi: 10.1001/archophthalmol.2011.2498. No abstract available.
   
   
7. Grieshaber MC, Flammer J / Is the medication used to achieve the target intraocular pressure in glaucoma therapy of relevance? – an exemplary analysis on the basis of two beta-blockers / Prog Retin eye Res. 29(1):79-93 / 2010.
   
   
8. Grieshaber MC: Advanced Glaucoma Surgery with focus on Schlemm’s canal. European Review of Ophthalmology. Vol. 3 (2): 40-43 / 2010.
   
   
9. Mozaffarieh M, Grieshaber MC, Orgül S, Flammer J. The potential value of natural antioxidative treatment in glaucoma / Surv Ophthalmol. 53(5):479-505. Review / 2008.
   
   
10. Mozaffarieh M, Grieshaber MC, Flammer J: Oxygen and blood flow: players in the pathogenesis of glaucoma. Mol Vis. 31;14:224-33 / 2008.
    
    
11. Müller K., Grieshaber MC, Orgül S: [Rifabutin-associated with bilateral uveitis in an HIV negative patient]. / Klin Monatsbl Augenheilkd. / 225(5):448-50 / 2008.
12. Grieshaber MC, Flammer J: Fundamental sciences in glaucoma. Introduction. / Surv Ophthalmol. 52 Suppl 2:S99-S100. Review / 2007.
    
    
13. Grieshaber MC, Mozaffarieh M, Flammer J: What is the link between vascular dysregulation and glaucoma? Surv Ophthalmol. 52 Suppl 2:S144-54. Review / 2007.
    
    
14. Grieshaber MC, Flammer J: Does the blood-brain barrier play a role in Glaucoma? / Surv Ophthalmol. / 52 Suppl 2:S115-21. Review / 2007.
    
    
15. Grieshaber MC, Dubler B, Knodel C, Killer HE, Flammer J, Orgül S: Retrobulbar blood flow in idiopathic dilated episcleral veins and glaucoma. Klin Monatsbl Augenheilkd. / 224(4):320-3 / 2007
    
    
16. Grieshaber MC, Staub JJ, Flammer J: The potential role of testosterone in central serous chorioretinopathy. Br J Ophthalmol./ 91(1):118-9 /2007.
    
    
17. Grieshaber MC, Terhorst T, Flammer J: The pathogenesis of optic disc splinter haemorrhages: a new hypothesis. Acta Ophthalmol Scand. 84(1):62-8 / 2006.
    
    
18. Grieshaber MC, Orgul S, Bruder E, Hadziselimovic F, Flammer J: Congenital iris ectropion and glaucoma associated with intestinal neuronal dysplasia: a manifestation of a neural crest syndrome. Arch Ophthalmol. 124(10):1495-7 / 2006.
    
    
19. Grieshaber MC, Flammer J: Blood flow in glaucoma. Curr Opin Ophthalmol. 16(2):79-83. Review / 2005.
    
    

Other publications

1. Grieshaber MC: Canaloplasty on the rise, Augenspiegel, 1-8, 09-2011
   
   
2. Grieshaber MC, John T: Canaloplasty offers an alternative to trabeculectomy, Ocular Surgery News, US Edition, 4-8, Vol 29, N° 18, 2011
   
   
3. Grieshaber MC: Canaloplasty: A Step-by-Step Approach, Techniques in Ophthalmology. 9(3):76-83, September 2011.
   
   
4. Grieshaber MC: Canaloplasty heralds a new era in glaucoma surgery, Ophthalmology Times Europe, 1/5; 39-42 / 2011
   
   
5. Grieshaber MC, Stegmann R: Schlemm’s Canal Surgery- Physiological Outflow Pathway Re-established / Highlights of Ophthalmology, Vol. 38, Nº 4: 8-11 / 2010
   
   
6. Peckar C, Grieshaber MC:. It’s never too late to learn new skills – Can introducing canaloplasty into a practice really make a difference? Ophthalmology Times Europe, 1/5/ 2009
   
   
7. Grieshaber MC, Flammer J: Clinical signs of retinal glial cell activation in glaucoma patients. SE Eur J Ophthalmol 1(1/2):1-6 / 2006

    

Book chapters, Reviews, Books

1. Grieshaber MC, Orgül S, Flammer J (Eds.): Glaucoma Therapy: State of the Art. ACEO, Basel, Switzerland 2009.
   
   
2. Meyer P, Grieshaber MC: Clinical pathological phenomenology of glaucoma. In Glaucoma Therapy: State of the Art. ACEO, Basel, Switzerland 2009.
   
   
3. Grieshaber MC: The concept of non-penetrating glaucoma surgery. In Glaucoma Therapy: State of the Art. ACEO, Basel, Switzerland 2009.
   
   
4. Stegmann R, Pienaar A, Grieshaber MC: Schlemm’s canal surgery: restoring physiological aqueous outflow. In Glaucoma Therapy: State of the Art. ACEO, Basel, Switzerland 2009.
   
   
5. Orgül S, Grieshaber MC: Perioperative care of the filtering surgery. In Glaucoma Therapy: State of the Art. ACEO, Basel, Switzerland 2009.
   
   
6. Gugleta K, Kavroulaki D, Grieshaber MC, Flammer J, Orgül S: Laser in glaucoma: classic techniques. In Glaucoma Therapy: State of the Art. ACEO, Basel, Switzerland 2009
   
   
7. Grieshaber MC, Boltshauser E, Niemeyer G. Leber’s congenital amaurosis. Clinical
   heterogeneity and electroretinography in 27 patients. In: Hollyfield X, et al. (eds) / Retinal degenerative diseases and experimental therapy. New York: New York: Kluwer Academic/Plenum Publishers / 95-104 / 1999.